This message was edited by seelangui on 21-Jul-2025 at 5:13 PM
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
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bishan st 13 got one big supplier kena caught right ?? 6 tonnes of supplies
Yup maybe the stall nearby no break out yet
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
http://forums.asianbookie.com/viewmessages.cfm?Forum=45&Topic=2112557
bishan st 13 got one big supplier kena caught right ?? 6 tonnes of supplies
There very quiet at night maybe at night many ppl have been there 😂
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
http://forums.asianbookie.com/viewmessages.cfm?Forum=45&Topic=2112557
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
http://forums.asianbookie.com/viewmessages.cfm?Forum=45&Topic=2112557
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
http://forums.asianbookie.com/viewmessages.cfm?Forum=45&Topic=2112557
General anesthesia fundamentally alters neuronal activity, leading to unconsciousness by disrupting communication between neurons in different brain regions.This disruption is not simply a reduction in overall activity, but a change in how neurons fire, often involving increased synchrony and altered patterns of electrical activity.
Here's a more detailed look:
1. Disrupting Communication:
Altered Oscillations:
Anesthetics cause brain circuits to change their oscillation patterns, preventing neurons from effectively communicating with each other.
Synchronized Activity:
Different anesthetics can induce distinct patterns of activity in neurons, but some, like those in layer 5 pyramidal neurons, show synchronized activity across all neurons of that type during anesthesia.
Reduced Information Output:
This synchronization can restrict the flow of information within the cortex and from the cortex to other brain regions, contributing to unconsciousness.
2. Impact on Neuron Firing:
Decreased Firing Rates:Anesthesia often decreases the overall firing rate of neurons.
Increased Synchronization:Neurons tend to fire in a more synchronized pattern, which can reduce the diversity of information being processed.
Altered Responses to Stimuli:Sensory responses, like those in the visual cortex, can be suppressed or altered during anesthesia.
3. Mechanisms of Action:
GABAergic Inhibition:
Anesthetics can enhance the activity of GABA receptors, which are involved in inhibitory neurotransmission, leading to reduced neuronal excitability.
NMDA Receptor Antagonism:
Some anesthetics can block NMDA receptors, which are crucial for excitatory neurotransmission, further contributing to the overall reduction in neuronal activity.
Calcium Signaling:
Disruptions in calcium signaling, which is vital for neuronal function and development, can also play a role in the effects of anesthesia.
4. Potential Long-Lasting Effects:
Developmental Neurotoxicity:
In young brains, anesthesia can potentially lead to neuroapoptosis (programmed cell death) and impairments in neuronal communication.
Cognitive Impairment:
In aged brains, anesthesia can be a risk factor for long-lasting cognitive impairments.
5. Nerve Damage:
Pressure-Related Damage:
During surgery, prolonged pressure on nerves can occur, especially when patients are under general anesthesia and cannot feel the pressure.
Nerve Injury:
While rare, nerve damage can occur during anesthesia, potentially leading to temporary or permanent neuropathic pain, numbness, or weakness.
In summary, general anesthesia affects neurons by altering their electrical activity, disrupting communication between brain regions, and potentially impacting neuronal development and function.These effects are complex and can vary depending on the specific anesthetic agent, the brain region, and the individual.
No cured also🥶 better stay away from them Ppl caught would be scared
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
http://forums.asianbookie.com/viewmessages.cfm?Forum=45&Topic=2112557
Yup better stay away from them especially on aircon room & transport 🥶
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
http://forums.asianbookie.com/viewmessages.cfm?Forum=45&Topic=2112557
My current Mission is keep wining until S_P 斗/close shop use main & sub method unit 1 unit= $20:
Use main bet as base the rest side bet to add on to max win or more Name it Eye jackpot system 南神眼
betting records at
http://forums.asianbookie.com/viewmessages.cfm?Forum=45&Topic=2112557
Man Seen Rolling on Road in Distress, Suspected of Using KPod Vape A disturbing scene recently unfolded along a busy road in Singapore, where a young man was caught on video in a state of severe distress — unable to stand, and visibly disoriented as he rolled around on the ground. Onlookers were stunned as the incident quickly escalated, with many speculating that the cause was linked to the growing misuse of KPod vape devices.
The man, whose identity remains unknown, was seen stumbling before collapsing entirely. Witnesses described him as twitching and groaning while clutching his body. He was reportedly incoherent and unresponsive to those trying to help. One bystander said, “It was like his body couldn’t control itself. He kept shaking, and his eyes looked empty.”
Passers-by quickly stepped in to call emergency services. While official confirmation on the cause is still pending, many who witnessed the incident believe it may be linked to the use of KPods — a brand of e-vaporisers that have become increasingly popular among youths despite being illegal in Singapore
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